Some of our clinical-academic activities:
- Multidisciplinary meeting
All cases being considered for surgery are discussed among a board of specialists, in which all teams involved in the management of liver diseases take part: liver surgery, liver transplant, medical oncology, hepatology, diagnostic and interventional radiology.
Meetings take place at ICESP (6th floor amphitheater) and they occur every Tuesday morning 8 a.m. – 10 a.m. The meeting is open to all interested healthcare professionals and students.
- Journal Club
Monthly the Liver Surgery Unit staff meets our students and residents in order to discuss important papers on Liver Surgery. The Journal Club promotes critical analysis of published papers and helps learners to build knowledge and update concepts in liver surgery.
Our 2016 chronogram and suggested readings are as follows:
January/2016 – Hepatocellular adenoma
Agrawal S, Agarwal S, Arnason T, Saini S, Belghiti J. Management of Hepatocellular Adenoma: Recent Advances. Clin Gastroenterol Hepatol. 2015 Jul;13(7):1221-30.
Zucman-Rossi J, Jeannot E, Nhieu JT, Scoazec JY, Guettier C, Rebouissou S, Bacq Y, Leteurtre E, Paradis V, Michalak S, Wendum D, Chiche L, Fabre M, Mellottee L, Laurent C, Partensky C, Castaing D, Zafrani ES, Laurent-Puig P, Balabaud C, Bioulac-Sage P. Genotype-phenotype correlation in hepatocellular adenoma: new classification and relationship with HCC. Hepatology. 2006 Mar;43(3):515-24.
February/2016 – Intra-hepatic biliary stones
Erlinger S. Low phospholipid-associated cholestasis and cholelithiasis. Clin Res Hepatol Gastroenterol. 2012 Sep;36 Suppl 1:S36-40.
Herman P, Perini MV, Pugliese V, Pereira JC, Machado MA, Saad WA, D’Albuquerque LA, Cecconello I. Does bilioenteric anastomosis impair results of liver resection in primary intrahepatic lithiasis? World J Gastroenterol. 2010 Jul 21;16(27):3423-6.
March/2016 – Hilar cholangiocarcinoma
Poruk KE, Pawlik TM, Weiss MJ. Perioperative Management of Hilar Cholangiocarcinoma. J Gastrointest Surg. 2015 Oct;19(10):1889-99.
Neuhaus P, Thelen A, Jonas S, Puhl G, Denecke T, Veltzke-Schlieker W, Seehofer D. Oncological superiority of hilar en bloc resection for the treatment of hilar cholangiocarcinoma. Ann Surg Oncol. 2012 May;19(5):1602-8.
April/2016 – Gallbladder carcinoma
Pawlik TM, Gleisner AL, Vigano L, Kooby DA, Bauer TW, Frilling A, Adams RB, Staley CA, Trindade EN, Schulick RD, Choti MA, Capussotti L. Incidence of finding residual disease for incidental gallbladder carcinoma: implications for re-resection. J Gastrointest Surg. 2007 Nov;11(11):1478-86;
Wernberg JA, Lucarelli DD. Gallbladder Cancer. Surg Clin North Am. 2014 Apr;94(2):343-60.
May/2016 – Hepatic neuroendocrine tumors metastases
Mayo SC, de Jong MC, Pulitano C, Clary BM, Reddy SK, Gamblin TC, Celinksi SA, Kooby DA, Staley CA, Stokes JB, Chu CK, Ferrero A, Schulick RD, Choti MA, Mentha G, Strub J, Bauer TW, Adams RB, Aldrighetti L, Capussotti L, Pawlik TM. Surgical management of hepatic neuroendocrine tumor metastasis: results from an international multi-institutional analysis. Ann Surg Oncol. 2010 Dec;17(12):3129-36.
Frilling A, Clift AK. Therapeutic strategies for neuroendocrine liver metastases. Cancer. 2015 Apr 15;121(8):1172-86.
June/2016 – Noncolorectal nonendocrine liver metastases
Adam R, Chiche L, Aloia T, Elias D, Salmon R, Rivoire M, Jaeck D, Saric J, Le Treut YP, Belghiti J, Mantion G, Mentha G; Association Française de Chirurgie. Hepatic resection for noncolorectal nonendocrine liver metastases: analysis of 1,452 patients and development of a prognostic model. Ann Surg. 2006 Oct;244(4):524-35.
Page AJ, Weiss MJ, Pawlik TM. Surgical management of noncolorectal cancer liver metastases. Cancer. 2014 Oct 15;120(20):3111-21.
July/2016 – Surgical Technique
Liddo G, Buc E, Nagarajan G, Hidaka M, Dokmak S, Belghiti J. The liver hanging manoeuvre. HPB (Oxford). 2009 Jun;11(4):296-305.
Lesurtel M, Selzner M, Petrowsky H, McCormack L, Clavien PA. How should transection of the liver be performed?: a prospective randomized study in 100 consecutive patients: comparing four different transection strategies. Ann Surg. 2005 Dec;242(6):814-22
August/2016 – Tumor ablation techniques
Wells SA, Hinshaw JL, Lubner MG, Ziemlewicz TJ, Brace CL, Lee FT Jr. Liver Ablation: Best Practice. Radiol Clin North Am. 2015 Sep;53(5):933-71.
September/2016 – Hepatocellular carcinoma (I)
Llovet JM, Fuster J, Bruix J. Intention-to-treat analysis of surgical treatment for early hepatocellular carcinoma: resection versus transplantation. Hepatology. 1999 Dec;30(6):1434-40.
Eguchi S, Kanematsu T, Arii S, Okazaki M, Okita K, Omata M, Ikai I, Kudo M, Kojiro M, Makuuchi M, Monden M, Matsuyama Y, Nakanuma Y, Takayasu K. Comparison of the outcomes between an anatomical subsegmentectomy and a non-anatomical minor hepatectomy for single hepatocellular carcinomas based on a Japanese nationwide survey. Surgery. 2008 Apr;143(4):469-75.
October/2016 – Hepatocellular carcinoma (II)
Truty MJ, Vauthey JN. Surgical resection of high-risk hepatocellular carcinoma: patient selection, preoperative considerations, and operative technique. Ann Surg Oncol. 2010 May;17(5):1219-25.
Forner A, Reig ME, de Lope CR, Bruix J. Current strategy for staging and treatment: the BCLC update and future prospects. Semin Liver Dis. 2010 Feb;30(1):61-74.
November/2016 – Colorectal cancer liver metastases (I)
Mentha G, Majno PE, Andres A, Rubbia-Brandt L, Morel P, Roth AD. Neoadjuvant chemotherapy and resection of advanced synchronous liver metastases before treatment of the colorectal primary. Br J Surg. 2006 Jul;93(7):872-8.
Lam VW, Laurence JM, Pang T, Johnston E, Hollands MJ, Pleass HC, Richardson AJ. A systematic review of a liver-first approach in patients with colorectal cancer and synchronous colorectal liver metastases. HPB (Oxford). 2014 Feb;16(2):101-8.
December/2016 – Colorectal cancer liver metastases (II)
Benoist S, Brouquet A, Penna C, Julié C, El Hajjam M, Chagnon S, Mitry E, Rougier P, Nordlinger B. Complete response of colorectal liver metastases after chemotherapy: does it mean cure? J Clin Oncol. 2006 Aug 20;24(24):3939-45.
Bischof DA, Clary BM, Maithel SK, Pawlik TM. Surgical management of disappearing colorectal liver metastases. Br J Surg. 2013 Oct;100(11):1414-20.
- Liver Club
The Sao Paulo State Medical Council (CREMESP) promotes a monthly meeting between the most important academic liver surgery units of our state. Clinical cases are discussed by a multidisciplinary team with participants from University of Sao Paulo Medical School, Federal University of Sao Paulo and Santa Casa Medical Sciences School.
Meetings take place at the Sao Paulo State Medical Council (CREMESP) every month´s first Tuesday, beginning 10 a.m. and are broadcasted through webconference to other important academic institutions in the State of Sao Paulo.
- Post graduation
The Liver Surgery Unit is committed to surgical research and development of surgical knowledge. It takes active part on our institution´s post-graduation program, helping surgeons to obtain their masters´ and doctors´ degrees.
- Medical Students Academic Liver League
Medical School Students willing to develop their interest in liver surgery are welcome to participate in our Liver League. The League is planned to offer the experience of liver surgery in many fronts:
Mondays: weekly scientific meeting (regular classes and scientific papers discussion);
Wednesday (morning): liver clinic;
Wednesday (afternoon): wet lab (porcine model experimental training);
Medical students involved with the League also engage on scientific papers production.